Metabolic Alterations associated with T2D are very well characterised by epidemiological and research primarily based studies. The pathogenesis and progression of T2D is ascribed to 4 mechanisms; improved Highly developed glycation finish merchandise (AGE) development, enhanced polyol pathway flux, activation of protein kinase C (PKC) isoforms, and increased hexosamine pathway https://www.directivepublications.org/journal-of-diabetology-research/